Dolphin Sutures manufactures antibacterial polyglactin 910 suture with broad spectrum antibacterial agent Chlorhexidine.
Chlorhexidine's antimicrobial effects are associated with the attractions between chlorhexldine and negatively charged bacterial cells. After chlorhexidine is absorbed onto the organism's cell wall, it disrupts the integrity of the cell membrane and causes the leakage of intracellular components of the organisms.
Chlorhexidine shows better antimicrobial efficacy compared to Triclosan against Staphylococcus aureus (including methicillin-resistant Staphylococcus aureus), Enterococcus faecalis (including vancomycin-resistant Enterococcus), Streptococcus pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Clostridium perfringens, Haemophilus influenzae and Candida albicans. The microbicidal efficacy was determined in accordance with DIN EN 1040 and 1275 using S. aureus, P. aeruginosa and C. albicans.